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Sectors: Health, Innovation, Research

Beneficiaries: Research centres, Universities

Regions: Candidate countries, European Economic Area, European Union, Switzerland

Category: Call for Proposals

Additional info regions:

Horizon 2020 associated countries: Iceland, Norway, Albania, Bosnia and Herzegovina, North Macedonia, Montenegro, Serbia, Turkey, Israel, Moldova, Switzerland, Faroe Islands, Ukraine, Tunisia, Georgia, Armenia


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Responsible: European Commission


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FET – The Human Brain Project/Validation and interference – 2020
Funds for: attracting experts in model validation and establishing independent validation of brain models against empirical data

Priorities and funded actions:

* To build and apply workflows which will enable the identification of relevant data features and model parameters with quantitative diagnostic value, including a quantification of intra- and interindividual variability and model identifiability;
* To validate existing brain models against available experimental evidence; 
* To map model parameter variability in light of biological diversity

* Adapting model inference and inversion techniques to the validation needs of the HBP brain reference;
* Optimising the parameters by incorporating latest optimisation, data fitting, and dimensionality reduction methods

Among financed actions
* Workflows adapted to models and data in WP1;
* Validation workflows to brain models in WP1 to establish independent evaluation of model performance against large-scale, multidimensional data
* Adaptation and application of model inference and inversion techniques to enable quantitative responses to questions of predictive capacity of personalised brain models; 
* Workflows making critical, substantial contributions to the model validation in WP1 and develop tools
* Techniques of dimension reduction and manifold estimation to sample, extract and reconstruct intra- and inter-individual variability and degeneracy for the small detailed cohorts;
*  Methods could include Bayesian inference, machine learning, information theoretical approaches

Additional information
* This call for proposals is an open call for proposals

* Initial duration fo the action: 30 months

* Eligibility:
– Be either HBP partners or non-HBP partners;
– Be a group of partners or a consortium, including Human brain project partners and non-partners 
– Potential new partners could include Scientists, Developers and Engineers with expertise in the fields of model inference and validation;
– Be established in the EU Member States or Horizon 2020 associated countries

* For more information about eligibility criteria click here

* Actions must take place in the European Union