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HORIZON EUROPE – Cluster 1 – Health (Two stage – 2025) – 2025

Pillar 2 of the Horizon Europe programme aims to boost innovation, competitiveness, and employment in Europe through collaborative projects, international partnerships, and funding opportunities accessible to companies of all sizes and sectors.

2025-09-16
210 million euro
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Call synthesis

Call reference HORIZON-HLTH-2025-03-two-stage
Programme Horizon Europe
Institution European Commission
Sectors Employment Environment & Climate Health Research & Innovation Technology & Digital
Beneficiaries Association & NGO EU & International Organisation Large company (> 250 employees) Local Authority & Affiliated Entity Research centre & university State administration & affiliated entities Training organisation & school

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Call reference

HORIZON-HLTH-2025-03-two-stage



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Priorities and funded actions

Some Horizon Europe budgets are structured in response to policy ambitions (“destinations”) and deployed through calls for proposals targeting more specific thematic/sector (“Topics”). Thus, your application must be linked to a topic of a call for proposals.

Various categories of projects are eligible:

  • RIA, Research and Innovation Actions: Basic and applied research / Technology development and adoption / Testing and validation of a prototype in the laboratory ;
  • IA, Innovation Actions: Prototypes, tests, demonstrations, pilot projects, market placement. These actions may include limited R&D activities ;
  • CSA, Coordination and Support Actions: Networking, studies & conferences, communication, studies for new research infrastructures ;
  • MSCA, Marie Skłodowska-Curie Actions / ERC individual grants: Training networks for researchers, Individual grants for experienced researchers, Staff exchange – mobility for researchers and non-scientific staff.

In addition, calls specify the categories of eligible beneficiaries:

  • Collaborative projects, composed of a coordinator and several partners organisations (consortium) ;
  • Single-beneficiary projects, involving a single organization ;
  • Individual scholarships, open to natural persons in their own name with their home institution.

TOPICS:

Forthcoming

  • HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: Improving the quality of life of persons with intellectual disabilities and their
    families
  • HORIZON-HLTH-2025-03-ENVHLTH-01-two-stage: The impact of pollution on the development and progression of brain diseases and disorders
  • HORIZON-HLTH-2025-03-ENVHLTH-02-two-stage: Advancing knowledge on the impacts of micro- and nanoplastics on human health
  • HORIZON-HLTH-2025-03-DISEASE-02-two-stage: Advancing innovative interventions for mental, behavioural and neurodevelopmental disorders
  • HORIZON-HLTH-2025-03-IND-03-two-stage: Facilitating the conduct of multinational clinical studies of orphan devices and/or of highly innovative (“breakthrough”) devices

Additional information

Useful

Financement
  • Total budget of the call: 210 million euros
  • Budget per topic:
    • HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: 40 million euros
    • HORIZON-HLTH-2025-03-ENVHLTH-01-two-stage: 40 million euros
    • HORIZON-HLTH-2025-03-ENVHLTH-02-two-stage: 40 million euros
    • HORIZON-HLTH-2025-03-DISEASE-02-two-stage: 50 million euros
    • HORIZON-HLTH-2025-03-IND-03-two-stage: 40 million euros
  • Funding rate: up to 100% of the total eligible costs